High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children
Identifieur interne : 000A86 ( Main/Exploration ); précédent : 000A85; suivant : 000A87High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children
Auteurs : Kyly C. Whitfield [Canada] ; Geoffry Smith [Singapour] ; Chhoun Chamnan [Cambodge] ; Crystal D. Karakochuk [Canada] ; Prak Sophonneary [Cambodge] ; Khov Kuong [Cambodge, Danemark] ; Marjoleine Amma Dijkhuizen [Danemark] ; Rathavuth Hong [États-Unis] ; Jacques Berger [France] ; Tim J. Green [Australie] ; Frank Tammo Wieringa [France]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- analyse : Thiamine.
- épidémiologie : Cambodge, Carence en thiamine.
- Adolescent, Adulte, Adulte d'âge moyen, Attribution aléatoire, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Jeune adulte, Mâle, Nourrisson, Prévalence, Érythrocytes, Études transversales.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Thiamine.
- chemistry : Erythrocytes.
- epidemiology : Cambodia, Thiamine Deficiency.
- Adolescent, Adult, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Infant, Male, Middle Aged, Prevalence, Random Allocation, Young Adult.
Abstract
Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15–49 y) and their young children (6–69 mo).
Samples for this cross-sectional analysis were collected as part of a national micronutrient survey linked to the Cambodian Demographic and Health Survey (CDHS) 2014. One-sixth of households taking part in the CDHS were randomly selected and re-visited for additional blood sampling for eThDP analysis (719 women and 761 children). Thiamine status was assessed using different cut-offs from literature.
Women were mean (SD) 30 (6) y, and children (46% girls) were 41 (17) mo. Women had lower mean (95% CI) eThDP of 150 nmol/L (146–153) compared to children, 174 nmol/L (171–179;
There is a lack of consensus on thiamine status cut-offs; more research is required to set clinically meaningful cut-offs. Despite this, there is strong evidence of suboptimal thiamine status among Cambodian mothers and their children, with infants <12 mo at the highest risk. Based on eThDP from this nationally-representative sample, immediate action is required to address thiamine deficiency in Cambodia, and likely throughout Southeast Asia.
Url:
DOI: 10.1371/journal.pntd.0005814
PubMed: 28873391
PubMed Central: 5600402
Affiliations:
- Australie, Cambodge, Canada, Danemark, France, Singapour, États-Unis
- Hovedstaden, Languedoc-Roussillon, Maryland, Occitanie (région administrative)
- Copenhague, Montpellier
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002921
- to stream Pmc, to step Curation: 002771
- to stream Pmc, to step Checkpoint: 000267
- to stream PubMed, to step Corpus: 000513
- to stream PubMed, to step Curation: 000511
- to stream PubMed, to step Checkpoint: 000511
- to stream Ncbi, to step Merge: 004D99
- to stream Ncbi, to step Curation: 004D99
- to stream Ncbi, to step Checkpoint: 004D99
- to stream Main, to step Merge: 000A81
- to stream Main, to step Curation: 000A86
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children</title><author><name sortKey="Whitfield, Kyly C" sort="Whitfield, Kyly C" uniqKey="Whitfield K" first="Kyly C." last="Whitfield">Kyly C. Whitfield</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Geoffry" sort="Smith, Geoffry" uniqKey="Smith G" first="Geoffry" last="Smith">Geoffry Smith</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>International Life Sciences Institute (Southeast Asia Region), Singapore</addr-line></nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>International Life Sciences Institute (Southeast Asia Region)</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Essential Micronutrients Foundation, Singapore</addr-line></nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Essential Micronutrients Foundation</wicri:regionArea></affiliation></author><author><name sortKey="Chamnan, Chhoun" sort="Chamnan, Chhoun" uniqKey="Chamnan C" first="Chhoun" last="Chamnan">Chhoun Chamnan</name><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation></author><author><name sortKey="Karakochuk, Crystal D" sort="Karakochuk, Crystal D" uniqKey="Karakochuk C" first="Crystal D." last="Karakochuk">Crystal D. Karakochuk</name><affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Sophonneary, Prak" sort="Sophonneary, Prak" uniqKey="Sophonneary P" first="Prak" last="Sophonneary">Prak Sophonneary</name><affiliation wicri:level="1"><nlm:aff id="aff006"><addr-line>National Nutrition Programme, Maternal and Child Health Centre, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>National Nutrition Programme, Maternal and Child Health Centre, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation></author><author><name sortKey="Kuong, Khov" sort="Kuong, Khov" uniqKey="Kuong K" first="Khov" last="Kuong">Khov Kuong</name><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="aff007"><addr-line>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Dijkhuizen, Marjoleine Amma" sort="Dijkhuizen, Marjoleine Amma" uniqKey="Dijkhuizen M" first="Marjoleine Amma" last="Dijkhuizen">Marjoleine Amma Dijkhuizen</name><affiliation wicri:level="3"><nlm:aff id="aff007"><addr-line>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Hong, Rathavuth" sort="Hong, Rathavuth" uniqKey="Hong R" first="Rathavuth" last="Hong">Rathavuth Hong</name><affiliation wicri:level="2"><nlm:aff id="aff008"><addr-line>ICF International, Rockville, Maryland, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>ICF International, Rockville, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berger, Jacques" sort="Berger, Jacques" uniqKey="Berger J" first="Jacques" last="Berger">Jacques Berger</name><affiliation wicri:level="3"><nlm:aff id="aff009"><addr-line>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Green, Tim J" sort="Green, Tim J" uniqKey="Green T" first="Tim J." last="Green">Tim J. Green</name><affiliation wicri:level="1"><nlm:aff id="aff010"><addr-line>Healthy Mothers, Babies and Children Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Healthy Mothers, Babies and Children Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff011"><addr-line>Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation></author><author><name sortKey="Wieringa, Frank Tammo" sort="Wieringa, Frank Tammo" uniqKey="Wieringa F" first="Frank Tammo" last="Wieringa">Frank Tammo Wieringa</name><affiliation wicri:level="3"><nlm:aff id="aff009"><addr-line>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28873391</idno><idno type="pmc">5600402</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600402</idno><idno type="RBID">PMC:5600402</idno><idno type="doi">10.1371/journal.pntd.0005814</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">002921</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002921</idno><idno type="wicri:Area/Pmc/Curation">002771</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002771</idno><idno type="wicri:Area/Pmc/Checkpoint">000267</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000267</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000513</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000513</idno><idno type="wicri:Area/PubMed/Curation">000511</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000511</idno><idno type="wicri:Area/PubMed/Checkpoint">000511</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000511</idno><idno type="wicri:Area/Ncbi/Merge">004D99</idno><idno type="wicri:Area/Ncbi/Curation">004D99</idno><idno type="wicri:Area/Ncbi/Checkpoint">004D99</idno><idno type="wicri:doubleKey">1935-2727:2017:Whitfield K:high:prevalence:of</idno><idno type="wicri:Area/Main/Merge">000A81</idno><idno type="wicri:Area/Main/Curation">000A86</idno><idno type="wicri:Area/Main/Exploration">000A86</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children</title><author><name sortKey="Whitfield, Kyly C" sort="Whitfield, Kyly C" uniqKey="Whitfield K" first="Kyly C." last="Whitfield">Kyly C. Whitfield</name><affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Applied Human Nutrition, Mount Saint Vincent University, Halifax, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Geoffry" sort="Smith, Geoffry" uniqKey="Smith G" first="Geoffry" last="Smith">Geoffry Smith</name><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>International Life Sciences Institute (Southeast Asia Region), Singapore</addr-line></nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>International Life Sciences Institute (Southeast Asia Region)</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff003"><addr-line>Essential Micronutrients Foundation, Singapore</addr-line></nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Essential Micronutrients Foundation</wicri:regionArea></affiliation></author><author><name sortKey="Chamnan, Chhoun" sort="Chamnan, Chhoun" uniqKey="Chamnan C" first="Chhoun" last="Chamnan">Chhoun Chamnan</name><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation></author><author><name sortKey="Karakochuk, Crystal D" sort="Karakochuk, Crystal D" uniqKey="Karakochuk C" first="Crystal D." last="Karakochuk">Crystal D. Karakochuk</name><affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia, Canada</addr-line></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Food, Nutrition, and Health, University of British Columbia, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Sophonneary, Prak" sort="Sophonneary, Prak" uniqKey="Sophonneary P" first="Prak" last="Sophonneary">Prak Sophonneary</name><affiliation wicri:level="1"><nlm:aff id="aff006"><addr-line>National Nutrition Programme, Maternal and Child Health Centre, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>National Nutrition Programme, Maternal and Child Health Centre, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation></author><author><name sortKey="Kuong, Khov" sort="Kuong, Khov" uniqKey="Kuong K" first="Khov" last="Kuong">Khov Kuong</name><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh, Cambodia</addr-line></nlm:aff><country xml:lang="fr">Cambodge</country><wicri:regionArea>Department of Post-Harvest Technologies and Quality Control, Fisheries Administration, Ministry of Agriculture, Forestry and Fisheries, Phnom Penh</wicri:regionArea><wicri:noRegion>Phnom Penh</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="aff007"><addr-line>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Dijkhuizen, Marjoleine Amma" sort="Dijkhuizen, Marjoleine Amma" uniqKey="Dijkhuizen M" first="Marjoleine Amma" last="Dijkhuizen">Marjoleine Amma Dijkhuizen</name><affiliation wicri:level="3"><nlm:aff id="aff007"><addr-line>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark</addr-line></nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Nutrition, Exercise and Sports, Copenhagen University, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Hong, Rathavuth" sort="Hong, Rathavuth" uniqKey="Hong R" first="Rathavuth" last="Hong">Rathavuth Hong</name><affiliation wicri:level="2"><nlm:aff id="aff008"><addr-line>ICF International, Rockville, Maryland, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>ICF International, Rockville, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berger, Jacques" sort="Berger, Jacques" uniqKey="Berger J" first="Jacques" last="Berger">Jacques Berger</name><affiliation wicri:level="3"><nlm:aff id="aff009"><addr-line>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Green, Tim J" sort="Green, Tim J" uniqKey="Green T" first="Tim J." last="Green">Tim J. Green</name><affiliation wicri:level="1"><nlm:aff id="aff010"><addr-line>Healthy Mothers, Babies and Children Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Healthy Mothers, Babies and Children Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff011"><addr-line>Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia, Australia</addr-line></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Discipline of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation></author><author><name sortKey="Wieringa, Frank Tammo" sort="Wieringa, Frank Tammo" uniqKey="Wieringa F" first="Frank Tammo" last="Wieringa">Frank Tammo Wieringa</name><affiliation wicri:level="3"><nlm:aff id="aff009"><addr-line>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier, France</addr-line></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Institute of Research for Development (IRD), UMR-204, IRD-UM-SupAgro, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author></analytic><series><title level="j">PLoS Neglected Tropical Diseases</title><idno type="ISSN">1935-2727</idno><idno type="eISSN">1935-2735</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Cambodia (epidemiology)</term><term>Child</term><term>Child, Preschool</term><term>Cross-Sectional Studies</term><term>Erythrocytes (chemistry)</term><term>Female</term><term>Humans</term><term>Infant</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Random Allocation</term><term>Thiamine (analysis)</term><term>Thiamine Deficiency (epidemiology)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Attribution aléatoire</term><term>Cambodge (épidémiologie)</term><term>Carence en thiamine (épidémiologie)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nourrisson</term><term>Prévalence</term><term>Thiamine (analyse)</term><term>Érythrocytes ()</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Thiamine</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Thiamine</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Erythrocytes</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cambodia</term><term>Thiamine Deficiency</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Cambodge</term><term>Carence en thiamine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Child</term><term>Child, Preschool</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Infant</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Random Allocation</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Attribution aléatoire</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nourrisson</term><term>Prévalence</term><term>Érythrocytes</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="sec001"><title>Background</title><p>Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15–49 y) and their young children (6–69 mo).</p></sec><sec id="sec002"><title>Methodology/Principle findings</title><p>Samples for this cross-sectional analysis were collected as part of a national micronutrient survey linked to the Cambodian Demographic and Health Survey (CDHS) 2014. One-sixth of households taking part in the CDHS were randomly selected and re-visited for additional blood sampling for eThDP analysis (719 women and 761 children). Thiamine status was assessed using different cut-offs from literature.</p><p>Women were mean (SD) 30 (6) y, and children (46% girls) were 41 (17) mo. Women had lower mean (95% CI) eThDP of 150 nmol/L (146–153) compared to children, 174 nmol/L (171–179; <italic>P</italic> < 0.001). Using the most conservative cut-off of eThDP < 120 nmol/L, 27% of mothers and 15% of children were thiamine deficient, however prevalence rates of deficiency were as high as 78% for mothers and 58% for children using a cut-off of < 180 nmol/L. Thiamine deficiency was especially prevalent among infants aged 6–12 mo: 38% were deficient using the most conservative cut-off (< 120 nmol/L).</p></sec><sec id="sec003"><title>Conclusions/Significance</title><p>There is a lack of consensus on thiamine status cut-offs; more research is required to set clinically meaningful cut-offs. Despite this, there is strong evidence of suboptimal thiamine status among Cambodian mothers and their children, with infants <12 mo at the highest risk. Based on eThDP from this nationally-representative sample, immediate action is required to address thiamine deficiency in Cambodia, and likely throughout Southeast Asia.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lee, Hs" uniqKey="Lee H">HS Lee</name></author><author><name sortKey="Lee, Sa" uniqKey="Lee S">SA Lee</name></author><author><name sortKey="Shin, Hs" uniqKey="Shin H">HS Shin</name></author><author><name sortKey="Choi, Hm" uniqKey="Choi H">HM Choi</name></author><author><name sortKey="Kim, Sj" uniqKey="Kim S">SJ Kim</name></author><author><name sortKey="Kim, Hk" uniqKey="Kim H">HK Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lonsdale, D" uniqKey="Lonsdale D">D Lonsdale</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khounnorath, S" uniqKey="Khounnorath S">S Khounnorath</name></author><author><name sortKey="Chamberlain, K" uniqKey="Chamberlain K">K Chamberlain</name></author><author><name sortKey="Taylor, Am" uniqKey="Taylor A">AM Taylor</name></author><author><name sortKey="Soukaloun, D" uniqKey="Soukaloun D">D Soukaloun</name></author><author><name sortKey="Mayxay, M" uniqKey="Mayxay M">M Mayxay</name></author><author><name sortKey="Lee, Sj" uniqKey="Lee S">SJ Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soukaloun, D" uniqKey="Soukaloun D">D Soukaloun</name></author><author><name sortKey="Lee, Sj" uniqKey="Lee S">SJ Lee</name></author><author><name sortKey="Chamberlain, K" uniqKey="Chamberlain K">K Chamberlain</name></author><author><name sortKey="Taylor, Am" uniqKey="Taylor A">AM Taylor</name></author><author><name sortKey="Mayxay, M" uniqKey="Mayxay M">M Mayxay</name></author><author><name sortKey="Sisouk, K" uniqKey="Sisouk K">K Sisouk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coats, D" uniqKey="Coats D">D Coats</name></author><author><name sortKey="Shelton Dodge, K" uniqKey="Shelton Dodge K">K Shelton-Dodge</name></author><author><name sortKey="Ou, K" uniqKey="Ou K">K Ou</name></author><author><name sortKey="Khun, V" uniqKey="Khun V">V Khun</name></author><author><name sortKey="Seab, S" uniqKey="Seab S">S Seab</name></author><author><name sortKey="Sok, K" uniqKey="Sok K">K Sok</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luxemburger, C" uniqKey="Luxemburger C">C Luxemburger</name></author><author><name sortKey="White, Nj" uniqKey="White N">NJ White</name></author><author><name sortKey="Ter Kuile, F" uniqKey="Ter Kuile F">F ter Kuile</name></author><author><name sortKey="Singh, Hm" uniqKey="Singh H">HM Singh</name></author><author><name sortKey="Allier Frachon, I" uniqKey="Allier Frachon I">I Allier-Frachon</name></author><author><name sortKey="Ohn, M" uniqKey="Ohn M">M Ohn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barennes, H" uniqKey="Barennes H">H Barennes</name></author><author><name sortKey="Sengkhamyong, K" uniqKey="Sengkhamyong K">K Sengkhamyong</name></author><author><name sortKey="Rene, Jp" uniqKey="Rene J">JP René</name></author><author><name sortKey="Phimmasane, M" uniqKey="Phimmasane M">M Phimmasane</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bemeur, C" uniqKey="Bemeur C">C Bemeur</name></author><author><name sortKey="Butterworth, Rf" uniqKey="Butterworth R">RF Butterworth</name></author><author><name sortKey="Ross, Ac" uniqKey="Ross A">AC Ross</name></author><author><name sortKey="Calallero, B" uniqKey="Calallero B">B Calallero</name></author><author><name sortKey="Cousins, Rj" uniqKey="Cousins R">RJ Cousins</name></author><author><name sortKey="Tucker, Kl" uniqKey="Tucker K">KL Tucker</name></author><author><name sortKey="Ziegler, Tr" uniqKey="Ziegler T">TR Ziegler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Lh" uniqKey="Allen L">LH Allen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ortega, Rm" uniqKey="Ortega R">RM Ortega</name></author><author><name sortKey="Martinez, Rm" uniqKey="Martinez R">RM Martínez</name></author><author><name sortKey="Andres, P" uniqKey="Andres P">P Andrés</name></author><author><name sortKey="Marin Arias, L" uniqKey="Marin Arias L">L Marín-Arias</name></author><author><name sortKey="L Pez Sobaler, Am" uniqKey="L Pez Sobaler A">AM López-Sobaler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baker, H" uniqKey="Baker H">H Baker</name></author><author><name sortKey="Frank, O" uniqKey="Frank O">O Frank</name></author><author><name sortKey="Thomson, Ad" uniqKey="Thomson A">AD Thomson</name></author><author><name sortKey="Langer, A" uniqKey="Langer A">A Langer</name></author><author><name sortKey="Munves, Ed" uniqKey="Munves E">ED Munves</name></author><author><name sortKey="De Angelis, B" uniqKey="De Angelis B">B De Angelis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carpenter, Kj" uniqKey="Carpenter K">KJ Carpenter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mimouni Bloch, A" uniqKey="Mimouni Bloch A">A Mimouni-Bloch</name></author><author><name sortKey="Goldberg Stern, H" uniqKey="Goldberg Stern H">H Goldberg-Stern</name></author><author><name sortKey="Strausberg, R" uniqKey="Strausberg R">R Strausberg</name></author><author><name sortKey="Brezner, A" uniqKey="Brezner A">A Brezner</name></author><author><name sortKey="Heyman, E" uniqKey="Heyman E">E Heyman</name></author><author><name sortKey="Inbar, D" uniqKey="Inbar D">D Inbar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vanier, Nl" uniqKey="Vanier N">NL Vanier</name></author><author><name sortKey="Paraginski, Rt" uniqKey="Paraginski R">RT Paraginski</name></author><author><name sortKey="Berrios, Jdj" uniqKey="Berrios J">JDJ Berrios</name></author><author><name sortKey="Oliveira, Ldc" uniqKey="Oliveira L">LDC Oliveira</name></author><author><name sortKey="Elias, Mc" uniqKey="Elias M">MC Elias</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Khush, Gs" uniqKey="Khush G">GS Khush</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coates, Kj" uniqKey="Coates K">KJ Coates</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Porter, Sg" uniqKey="Porter S">SG Porter</name></author><author><name sortKey="Coats, D" uniqKey="Coats D">D Coats</name></author><author><name sortKey="Fischer, Pr" uniqKey="Fischer P">PR Fischer</name></author><author><name sortKey="Ou, K" uniqKey="Ou K">K Ou</name></author><author><name sortKey="Frank, El" uniqKey="Frank E">EL Frank</name></author><author><name sortKey="Sreang, P" uniqKey="Sreang P">P Sreang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keating, Em" uniqKey="Keating E">EM Keating</name></author><author><name sortKey="Nget, P" uniqKey="Nget P">P Nget</name></author><author><name sortKey="Kea, S" uniqKey="Kea S">S Kea</name></author><author><name sortKey="Kuong, S" uniqKey="Kuong S">S Kuong</name></author><author><name sortKey="Daly, L" uniqKey="Daly L">L Daly</name></author><author><name sortKey="Phearom, S" uniqKey="Phearom S">S Phearom</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Gibson, Rs" uniqKey="Gibson R">RS Gibson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Talwar, D" uniqKey="Talwar D">D Talwar</name></author><author><name sortKey="Davidson, H" uniqKey="Davidson H">H Davidson</name></author><author><name sortKey="Cooney, J" uniqKey="Cooney J">J Cooney</name></author><author><name sortKey="St Jo Eilly, D" uniqKey="St Jo Eilly D">D St Jo’Reilly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauberlich, He" uniqKey="Sauberlich H">HE Sauberlich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitfield, Kc" uniqKey="Whitfield K">KC Whitfield</name></author><author><name sortKey="Karakochuk, Cd" uniqKey="Karakochuk C">CD Karakochuk</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Mccann, A" uniqKey="Mccann A">A McCann</name></author><author><name sortKey="Talukder, A" uniqKey="Talukder A">A Talukder</name></author><author><name sortKey="Kroeun, H" uniqKey="Kroeun H">H Kroeun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitfield, Kc" uniqKey="Whitfield K">KC Whitfield</name></author><author><name sortKey="Green, Tj" uniqKey="Green T">TJ Green</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wieringa, Ft" uniqKey="Wieringa F">FT Wieringa</name></author><author><name sortKey="Dahl, M" uniqKey="Dahl M">M Dahl</name></author><author><name sortKey="Chamnan, C" uniqKey="Chamnan C">C Chamnan</name></author><author><name sortKey="Poirot, E" uniqKey="Poirot E">E Poirot</name></author><author><name sortKey="Kuong, K" uniqKey="Kuong K">K Kuong</name></author><author><name sortKey="Sophonneary, P" uniqKey="Sophonneary P">P Sophonneary</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, J" uniqKey="Lu J">J Lu</name></author><author><name sortKey="Frank, El" uniqKey="Frank E">EL Frank</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitfield, Kc" uniqKey="Whitfield K">KC Whitfield</name></author><author><name sortKey="Karakochuk, Cd" uniqKey="Karakochuk C">CD Karakochuk</name></author><author><name sortKey="Kroeun, H" uniqKey="Kroeun H">H Kroeun</name></author><author><name sortKey="Hampel, D" uniqKey="Hampel D">D Hampel</name></author><author><name sortKey="Sokhoing, L" uniqKey="Sokhoing L">L Sokhoing</name></author><author><name sortKey="Chan, Bb" uniqKey="Chan B">BB Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schrijver, J" uniqKey="Schrijver J">J Schrijver</name></author><author><name sortKey="Van Veelen, Bwc" uniqKey="Van Veelen B">BWC Van Veelen</name></author><author><name sortKey="Schreurs, Whp" uniqKey="Schreurs W">WHP Schreurs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baines, M" uniqKey="Baines M">M Baines</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilkinson, Tj" uniqKey="Wilkinson T">TJ Wilkinson</name></author><author><name sortKey="Hanger, Hc" uniqKey="Hanger H">HC Hanger</name></author><author><name sortKey="Elmslie, J" uniqKey="Elmslie J">J Elmslie</name></author><author><name sortKey="George, Pm" uniqKey="George P">PM George</name></author><author><name sortKey="Sainsbury, R" uniqKey="Sainsbury R">R Sainsbury</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Floridi, A" uniqKey="Floridi A">A Floridi</name></author><author><name sortKey="Pupita, M" uniqKey="Pupita M">M Pupita</name></author><author><name sortKey="Palmerini, Ca" uniqKey="Palmerini C">CA Palmerini</name></author><author><name sortKey="Fini, C" uniqKey="Fini C">C Fini</name></author><author><name sortKey="Fidanza, Aa" uniqKey="Fidanza A">AA Fidanza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bailey, Al" uniqKey="Bailey A">AL Bailey</name></author><author><name sortKey="Pinglas, Pm" uniqKey="Pinglas P">PM Pinglas</name></author><author><name sortKey="Weight, Aja" uniqKey="Weight A">AJA Weight</name></author><author><name sortKey="Southon, S" uniqKey="Southon S">S Southon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bailey, Al" uniqKey="Bailey A">AL Bailey</name></author><author><name sortKey="Maisey, S" uniqKey="Maisey S">S Maisey</name></author><author><name sortKey="Southon, S" uniqKey="Southon S">S Southon</name></author><author><name sortKey="Wright, Aja" uniqKey="Wright A">AJA Wright</name></author><author><name sortKey="Finglas, Pm" uniqKey="Finglas P">PM Finglas</name></author><author><name sortKey="Fulcher, Ra" uniqKey="Fulcher R">RA Fulcher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Warnock, Lg" uniqKey="Warnock L">LG Warnock</name></author><author><name sortKey="Prudhomme, Cr" uniqKey="Prudhomme C">CR Prudhomme</name></author><author><name sortKey="Wagner, C" uniqKey="Wagner C">C Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mancinelli, R" uniqKey="Mancinelli R">R Mancinelli</name></author><author><name sortKey="Ceccanti, M" uniqKey="Ceccanti M">M Ceccanti</name></author><author><name sortKey="Guiducci, Ms" uniqKey="Guiducci M">MS Guiducci</name></author><author><name sortKey="Sasso, Gf" uniqKey="Sasso G">GF Sasso</name></author><author><name sortKey="Sebastiani, G" uniqKey="Sebastiani G">G Sebastiani</name></author><author><name sortKey="Attilia, Ml" uniqKey="Attilia M">ML Attilia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bailey, Al" uniqKey="Bailey A">AL Bailey</name></author><author><name sortKey="Finglas, Pm" uniqKey="Finglas P">PM Finglas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Westhuyzen, J" uniqKey="Van Der Westhuyzen J">J van der Westhuyzen</name></author><author><name sortKey="Steyn, Np" uniqKey="Steyn N">NP Steyn</name></author><author><name sortKey="Icke, Gc" uniqKey="Icke G">GC Icke</name></author><author><name sortKey="Davis, Re" uniqKey="Davis R">RE Davis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schrijver, J" uniqKey="Schrijver J">J Schrijver</name></author><author><name sortKey="Pietrzik, K" uniqKey="Pietrzik K">K Pietrzik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raghavan, R" uniqKey="Raghavan R">R Raghavan</name></author><author><name sortKey="Ashour, Fs" uniqKey="Ashour F">FS Ashour</name></author><author><name sortKey="Bailey, R" uniqKey="Bailey R">R Bailey</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kauffman, G" uniqKey="Kauffman G">G Kauffman</name></author><author><name sortKey="Coats, D" uniqKey="Coats D">D Coats</name></author><author><name sortKey="Seab, S" uniqKey="Seab S">S Seab</name></author><author><name sortKey="Topazian, Md" uniqKey="Topazian M">MD Topazian</name></author><author><name sortKey="Fischer, Pr" uniqKey="Fischer P">PR Fischer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whitfield, Kc" uniqKey="Whitfield K">KC Whitfield</name></author><author><name sortKey="Karakochuk, Cd" uniqKey="Karakochuk C">CD Karakochuk</name></author><author><name sortKey="Kroeun, H" uniqKey="Kroeun H">H Kroeun</name></author><author><name sortKey="Sokhoing, L" uniqKey="Sokhoing L">L Sokhoing</name></author><author><name sortKey="Chan, Bb" uniqKey="Chan B">BB Chan</name></author><author><name sortKey="Borath, M" uniqKey="Borath M">M Borath</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcgready, R" uniqKey="Mcgready R">R McGready</name></author><author><name sortKey="Simpson, Ja" uniqKey="Simpson J">JA Simpson</name></author><author><name sortKey="Cho, T" uniqKey="Cho T">T Cho</name></author><author><name sortKey="Dubowitz, L" uniqKey="Dubowitz L">L Dubowitz</name></author><author><name sortKey="Changbumrung, S" uniqKey="Changbumrung S">S Changbumrung</name></author><author><name sortKey="Bohm, V" uniqKey="Bohm V">V Böhm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doung Ngern, P" uniqKey="Doung Ngern P">P Doung-ngern</name></author><author><name sortKey="Kesornsukhon, S" uniqKey="Kesornsukhon S">S Kesornsukhon</name></author><author><name sortKey="Kanlayanaphotporn, J" uniqKey="Kanlayanaphotporn J">J Kanlayanaphotporn</name></author><author><name sortKey="Wanadurongwan, S" uniqKey="Wanadurongwan S">S Wanadurongwan</name></author><author><name sortKey="Songchitsomboon, S" uniqKey="Songchitsomboon S">S Songchitsomboon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brannon, Pm" uniqKey="Brannon P">PM Brannon</name></author><author><name sortKey="Weaver, Cm" uniqKey="Weaver C">CM Weaver</name></author><author><name sortKey="Anderson, Cam" uniqKey="Anderson C">CAM Anderson</name></author><author><name sortKey="Donovan, Sm" uniqKey="Donovan S">SM Donovan</name></author><author><name sortKey="Murphy, Sp" uniqKey="Murphy S">SP Murphy</name></author><author><name sortKey="Yaktine, Al" uniqKey="Yaktine A">AL Yaktine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Said, Hm" uniqKey="Said H">HM Said</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manzetti, S" uniqKey="Manzetti S">S Manzetti</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author><author><name sortKey="Van Der Spoel, D" uniqKey="Van Der Spoel D">D van der Spoel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kerns, Jc" uniqKey="Kerns J">JC Kerns</name></author><author><name sortKey="Arundel, C" uniqKey="Arundel C">C Arundel</name></author><author><name sortKey="Chawla" uniqKey="Chawla">Chawla</name></author><author><name sortKey="Lakhmir, S" uniqKey="Lakhmir S">S Lakhmir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gibson, Ge" uniqKey="Gibson G">GE Gibson</name></author><author><name sortKey="Hirsch, Ja" uniqKey="Hirsch J">JA Hirsch</name></author><author><name sortKey="Fonzetti, P" uniqKey="Fonzetti P">P Fonzetti</name></author><author><name sortKey="Jordan, Bd" uniqKey="Jordan B">BD Jordan</name></author><author><name sortKey="Cirio, Rt" uniqKey="Cirio R">RT Cirio</name></author><author><name sortKey="Elder, J" uniqKey="Elder J">J Elder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harel, Y" uniqKey="Harel Y">Y Harel</name></author><author><name sortKey="Zuk, L" uniqKey="Zuk L">L Zuk</name></author><author><name sortKey="Guindy, M" uniqKey="Guindy M">M Guindy</name></author><author><name sortKey="Nakar, O" uniqKey="Nakar O">O Nakar</name></author><author><name sortKey="Lotan, D" uniqKey="Lotan D">D Lotan</name></author><author><name sortKey="Fattal Valevski, A" uniqKey="Fattal Valevski A">A Fattal-Valevski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fattal, I" uniqKey="Fattal I">I Fattal</name></author><author><name sortKey="Friedmann, N" uniqKey="Friedmann N">N Friedmann</name></author><author><name sortKey="Fattal Valevski, A" uniqKey="Fattal Valevski A">A Fattal-Valevski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuizon, Md" uniqKey="Kuizon M">MD Kuizon</name></author><author><name sortKey="Perlas, La" uniqKey="Perlas L">LA Perlas</name></author><author><name sortKey="Madriaga, Jr" uniqKey="Madriaga J">JR Madriaga</name></author><author><name sortKey="Cheong, Rl" uniqKey="Cheong R">RL Cheong</name></author><author><name sortKey="Desnacido, Ja" uniqKey="Desnacido J">JA Desnacido</name></author><author><name sortKey="Marcos, Jm" uniqKey="Marcos J">JM Marcos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gangolf, M" uniqKey="Gangolf M">M Gangolf</name></author><author><name sortKey="Czerniecki, J" uniqKey="Czerniecki J">J Czerniecki</name></author><author><name sortKey="Radermecker, M" uniqKey="Radermecker M">M Radermecker</name></author><author><name sortKey="Detry, O" uniqKey="Detry O">O Detry</name></author><author><name sortKey="Nisolle, M" uniqKey="Nisolle M">M Nisolle</name></author><author><name sortKey="Jouan, C" uniqKey="Jouan C">C Jouan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thurnham, Di" uniqKey="Thurnham D">DI Thurnham</name></author><author><name sortKey="Cathcart, Ae" uniqKey="Cathcart A">AE Cathcart</name></author><author><name sortKey="Livingstone, Mbe" uniqKey="Livingstone M">MBE Livingstone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elmadfa, I" uniqKey="Elmadfa I">I Elmadfa</name></author><author><name sortKey="Majchrzak, D" uniqKey="Majchrzak D">D Majchrzak</name></author><author><name sortKey="Rust, P" uniqKey="Rust P">P Rust</name></author><author><name sortKey="Genser, D" uniqKey="Genser D">D Genser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gibson, Rs" uniqKey="Gibson R">RS Gibson</name></author><author><name sortKey="Cavalli Sforza, T" uniqKey="Cavalli Sforza T">T Cavalli-Sforza</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>Cambodge</li><li>Canada</li><li>Danemark</li><li>France</li><li>Singapour</li><li>États-Unis</li></country><region><li>Hovedstaden</li><li>Languedoc-Roussillon</li><li>Maryland</li><li>Occitanie (région administrative)</li></region><settlement><li>Copenhague</li><li>Montpellier</li></settlement></list><tree><country name="Canada"><noRegion><name sortKey="Whitfield, Kyly C" sort="Whitfield, Kyly C" uniqKey="Whitfield K" first="Kyly C." last="Whitfield">Kyly C. Whitfield</name></noRegion><name sortKey="Karakochuk, Crystal D" sort="Karakochuk, Crystal D" uniqKey="Karakochuk C" first="Crystal D." last="Karakochuk">Crystal D. Karakochuk</name></country><country name="Singapour"><noRegion><name sortKey="Smith, Geoffry" sort="Smith, Geoffry" uniqKey="Smith G" first="Geoffry" last="Smith">Geoffry Smith</name></noRegion><name sortKey="Smith, Geoffry" sort="Smith, Geoffry" uniqKey="Smith G" first="Geoffry" last="Smith">Geoffry Smith</name></country><country name="Cambodge"><noRegion><name sortKey="Chamnan, Chhoun" sort="Chamnan, Chhoun" uniqKey="Chamnan C" first="Chhoun" last="Chamnan">Chhoun Chamnan</name></noRegion><name sortKey="Kuong, Khov" sort="Kuong, Khov" uniqKey="Kuong K" first="Khov" last="Kuong">Khov Kuong</name><name sortKey="Sophonneary, Prak" sort="Sophonneary, Prak" uniqKey="Sophonneary P" first="Prak" last="Sophonneary">Prak Sophonneary</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Kuong, Khov" sort="Kuong, Khov" uniqKey="Kuong K" first="Khov" last="Kuong">Khov Kuong</name></region><name sortKey="Dijkhuizen, Marjoleine Amma" sort="Dijkhuizen, Marjoleine Amma" uniqKey="Dijkhuizen M" first="Marjoleine Amma" last="Dijkhuizen">Marjoleine Amma Dijkhuizen</name></country><country name="États-Unis"><region name="Maryland"><name sortKey="Hong, Rathavuth" sort="Hong, Rathavuth" uniqKey="Hong R" first="Rathavuth" last="Hong">Rathavuth Hong</name></region></country><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Berger, Jacques" sort="Berger, Jacques" uniqKey="Berger J" first="Jacques" last="Berger">Jacques Berger</name></region><name sortKey="Wieringa, Frank Tammo" sort="Wieringa, Frank Tammo" uniqKey="Wieringa F" first="Frank Tammo" last="Wieringa">Frank Tammo Wieringa</name></country><country name="Australie"><noRegion><name sortKey="Green, Tim J" sort="Green, Tim J" uniqKey="Green T" first="Tim J." last="Green">Tim J. Green</name></noRegion><name sortKey="Green, Tim J" sort="Green, Tim J" uniqKey="Green T" first="Tim J." last="Green">Tim J. Green</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A86 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A86 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:5600402
|texte= High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28873391" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |